Aerosol transmitted COVID-19 virus (SARS-CoV-2) is infectious causing both symptomatic and asymptomatic infections. The viable COVID-19 virus transmission via air has occurred. Therefore, methods must be established to determine the viability of the virus and to disinfect it in air, surfaces, and on foodstuff. In this review article, we have discussed the pattern virus spread in bus, hospital, and cruise ship. The methods of reducing and eliminating the infection in household and public places have been suggested. The safety, efficacy, and phase 3 trials data published by major vaccine candidates Russian Gamaleya’s “Sputnik V”, Oxford University –AstraZeneca, CanSino Biologics, and Moderna Therapeutics have been included. The article is very useful to stop the COVID-19 pandemic spread and finally ending the pandemic.
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