Case Study

Ocular Manifestations of Donnai Barrow Syndrome

Ayoub Redouan
Hassan II University, Morocco
* Corresponding author
Hind Hamdani
Hassan II University, Morocco
Soukaina Amrani
Hassan II University, Morocco
Loubna El Maaloum
Hassan II University, Morocco
Bouchra Allali
Hassan II University, Morocco
Asmae El Kettani
Hassan II University, Morocco
DOI icon 10.24018/ejmed.2020.2.6.605

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Submitted 2020-12-06
Published 2020-12-16

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Table of Contents

Article Main Content

Donnai-Barrow syndrome is an autosomal recessive disease due to mutations in the LRP2 gene described by Donnai and Barrow in 1993. We report through this clinical case the various ophthalmologic and extraocular manifestations of Donnai Barrow syndrome which remains a very rare congenital malformation. High myopia is a risk factor for severe amblyopia and/or retinal detachment which requires a regular monitoring.

The management of this disabling disease is multidisciplinary, involving the ophthalmologist, the otorhinolaryngologist, the pediatrician and the psychiatrist.

Keywords: Donnai-Barraow syndrome, high myopia, amblyopia, retinal detachment

References

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