Distribution of ABO, Rhesus Factor Blood Phenotype and Haemoglobin Genotype among Antenatal Clinic Attendees in Anyigba, North Central Nigeria

##plugins.themes.bootstrap3.article.main##

  •   Simon P. O. Akogu

  •   Owemidu Idowu Olumorin

  •   Shedrack Egbunu Akor

Abstract


Background: In the practice of obstetrics and gynecology, the ABO and Rhesus factor (Rh) blood type are important. Blood typing for blood transfusion of compatible blood is very common in emergency and routine care. There is a scanty literature on the distribution of ABO and Rhesus blood types in Anyigba, (North central) Nigeria.




Objective: This study aims to determine the distribution of ABO blood and Rhesus blood group phenotypes and Hemoglobin genotypes among antenatal clinic attendees in a teaching hospital.




Methods: Antenatal records of attendees (October 2017 to September 2020) at the Kogi State University Teaching Hospital were retrieved and results of antenatal hematological investigations were collected using a structured tool.Bio data, ABO blood group, Rhesus group phenotype and Hemoglobin genotype were collected, inputted and analyzed using SPSS version 20.




Results: The mean age was 26 +/- 7years, blood group O is most prevalent,561 (53.6%) then A 276 (26.4%), B 189 (18.1%) and AB,21 (2%).1014 (96.4%) were Rhesus D positive, 33 (3.1%) were Rhesus D negative. For hemoglobin genotype, 786 (75.1%) were AA, 258 (24.6%) were AS, AC were 3 (0.3%).




Conclusion: The distribution of the ABO, the Rhesus (D) blood groups and hemoglobin genotypes are in concurrence with the findings of previous studies; Blood group O is the most prevalent and AB the least prevalent, Rhesus (D) positive in the population is high and the hemoglobin genotype AA is the most prevalent. There is no association between blood group phenotypes studied and the hemoglobin genotypes.



Keywords: ABO, antenatal clinic, attendees, Anyigba, genotype, Nigeria, rhesus factor

References

J. O. Ameand andO. Young, “A preliminary survey of the distribution of ABO and Rhesus blood groups in Trinidad,”Tropical and Geographical Medicine 7:375-8, 1955.

O. K. Chima, T. B. Mohammed, K. Aisha, S. A. Alhaji, B. M. Muhammed andA. H. Kwaru, “ABO and Rhesus blood groups among blood donors in Kano, North-Western Nigeria,”Nigerian Journal of Basic Clinical Sciences 9:11-3, 2021.

J. V. Dacie andS. M. Lewis,Practical hematology 9th ed. London: Churchill Livingstone, Harcourt Publishers Limited, 2001.

V. I. Iyawe, A. D. Igboroye andG. A. Akinyabi,“Preliminary survey of Rhesus inheritance and ABO blood groups in Nigerians,” Nigerian Journal of Physiological Sciences 15:18-9, 1999.

T. Korubo- Owiye andP. S. Igbigbi,“Distribution of ABO and Rhesus Genes among Socio- economic classes in port Harcourt, Nigeria,”Nigerian Journalof Physiological Sciences 10:22-8, 1994.

A. G. Kulkumi, B. Peter,D. Z. Ibazedor and A. F. Fleming, “The ABO and Rhesus groups in the north of Nigeria,”Annals of TropicalMedicine Parasitology 79:83-8, 1984.

E. E. Mathew and N. B. Godwin, “Distribution of ABO and Rhesus –D blood groups in the Benin area of Niger Delta: Implications for regional blood transfusion,”Asian Journal of Transfusion Science 2:3-5, 2008.

A. E. Mourant, A. C. Kopec and K. Donmainiewskisobezak,The distribution of blood groups and other polymorphisms 2nd ed. London: Oxford University Press;1968.

G. O. Ojo,O. O. Ajose- Clokes and O. O. Balogun, “Frequency distribution of ABO and Rhesus blood groups in the Urban population of Lagos,”Nigerian Journal of Physiological Science 3:3:79-83, 1987.

K. E. Onwukeme,“Blood group distribution in blood donors in a Nigerian population,”Nigeria Journal of Physiology Science 6:67-70, 1990.

S. Worlledge,S. E. Ogiemudia, C. O. Thomas, B. N. Ikoku and L. Luzzutto,“Blood group antigens and antibodies in Nigeria,”Annals of TropicalMedicine Parasitology 86:249-64, 1974.

O. Jahanpour, J. J. Pyuza, E. O. Ntiyakunze, A. Mremi and E. R. Shao, “ABO and Rhesus blood group distribution and frequency among blood donors at Kilimanjaro Christian Medical Center, Moshi, Tanzania,” BMC Research Notes 10, 738, 2017.

A. Z. Al-Riyami, A. Al-Marhoobi, S. Al-Hosni, S. Al Mahrooqi, M. Schmidt, S. O’brien and M. Al-Khabori, “Prevalence of red blood cell major blood group antigens and phenotypes among Omani blood donors,” Oman Medical Journal 34(6): 496, 2019.

M. D.Lungus,U.Y.Polit,O. U. Nnana, N. I. Vwandem and J. D. Damen, “Distribution of Hemoglobin Genotypes, ABO and Rhesus (D) blood groups among pregnant women in North Central Nigeria,”World Journal of pharmaceutical and Medical Research(wjpmr) 4(6): 54-58, 2018.

A. A. Adeyemi, A. O. Ladipo, O. A. Omolade, D. D. Ogbaro, “Frequency Distribution of Hemoglobin Variants among Teenagers,” British Journal of Medicine & Medical Research 14(4): 1-5, 2016.

Downloads

Download data is not yet available.

##plugins.themes.bootstrap3.article.details##

How to Cite
Akogu, S. P. O., Olumorin, O. I., & Akor, S. E. (2021). Distribution of ABO, Rhesus Factor Blood Phenotype and Haemoglobin Genotype among Antenatal Clinic Attendees in Anyigba, North Central Nigeria. European Journal of Medical and Health Sciences, 3(6), 11–13. https://doi.org/10.24018/ejmed.2021.3.6.954