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Human immunodeficiency virus (HIV) and Acquired immunodeficiency syndrome (AIDS) have been a major problem around the world, and various control have been put in place to tame this potentially life-threatening virus. The research aims to expose the relationship between HIV/AIDS and potable water. However, it is generally believed that the virus cannot be contacted through water, but the interface between HIV/AIDS may likely be influenced through scarcity of water. The data for this research was collected through administration of questionnaire to people leaving with HIV/AIDS (PLWHA) at major health institutions in the three senatorial districts in Ekiti state. The data collected were analyzed using statistical tools and the results show that 44.5% of the respondents believed that water availability can reduce the spread of HIV/AIDS infection around the study area. 84.5% of the respondents had an increased need of water after HIV infections. While 92.7% of the respondents agreed HIV positive people have increased need for better hygiene and sanitation. The study discovers that water, sanitation, hygiene and population are agents determining the spread of HIV/AIDS in the environment. Thus, planning and proper spread of infrastructure that support supply of potable water will reduce and control the virus.

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