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Depression can be compared to a fire that occurs in our head. Gradually, it burns what used to be pleasurable, leaving only the feeling of emptiness and sadness. It influences thoughts, emotions, thinking and affects the everyday activities. Depression is a disorder characterized by a constant state of sadness and hopelessness. Depressed person loses interest in any activity that is usually brings pleasure, as well as the inability to perform daily living activities. These symptoms should be permanent (at least two weeks). Bad mood once a month, with or without a reason, cannot immediately be called depression. This insidious disorder destroys relationships, impedes normal functioning and can even lead to job loss. Accumulation of problems, the lack of support from family members and the lack of skilled help can lead to even more devastating behaviour and even suicide. This review article discusses the problems associated with the treatment of depression and the impact of this problem on the lives of Nations. The value of antidepressants in the treatment process discussed in details.

References

  1. World Federation for Mental Health. (2012). Depression: A Global Crisis World Mental Health Day, October 10 2012. Available at: https://www.who.int/mental_health/management/depression/wfmh_paper_depression_wmhd_2012.pdf (Accessed on 1st May, 2020).
     Google Scholar
  2. Tsarkov, A., & Petlovanyi, P. The Role of Lamotrigine in the Treatment of Bipolar Depression. Available at: https://pdfs.semanticscholar.org/bd92/bbbe8a986a155e0684fd6f27569ebd895d6e.pdf (Accessed on 1st May, 2020).
     Google Scholar
  3. Tsarkov, A., & Petlovanyi, P. (2019). Neuropsychiatric Aspects of a Common Problem: Stroke. European Journal of Medical and Health Sciences, 1(3). https://doi.org/10.24018/ejmed.2019.1.3.64 Available at: https://pdfs.semanticscholar.org/e830/852f04b7b788300b6f23f295e10327c858e5.pdf (Accessed on 1st May, 2020).
     Google Scholar
  4. Mayo Clinic. Depression (major depressive disorder). Available at: https://www.mayoclinic.org/diseasesconditions/depression/symptoms-causes/syc-20356007 (Accessed on 2nd May, 2020).
     Google Scholar
  5. Tsarkov, A., & Petlovanyi, P. Depressive Disorder in Child Psychiatric Practice: A. The Health Press, 9. Available at: http://znphi.co.zm/thehealthpress/wp-content/uploads/2017/09/THPZ_V1_I5_May_final.3.pdf (Accessed on 2nd May, 2020).
     Google Scholar
  6. Petlovanyi, P., & Tsarkov, A. (2020). Child Schizophrenia: Theory and Practice. European Journal of Medical and Health Sciences, 2(1). https://doi.org/10.24018/ejmed.2020.2.1.160 Available at: https://pdfs.semanticscholar.org/ddda/4caaee5645fed79e1f16b74a2a84b92cd5ea.pdf (Accessed on 2nd May, 2020).
     Google Scholar
  7. Morton, D. (2019). Social Security Disability and SSI for Depression. Disability Secrets by NOLO. Available: https://www.disabilitysecrets.com/win-can-you-get-disability-for-depression.html (Accessed on 5th May, 2020).
     Google Scholar
  8. Tsarkov, A., & Petlovanyi, P. (2016). Bipolar Disorder in Child Psychiatric Practice: A Case Report. Medical Journal of Zambia, 43(1), 41-46. Available at:
     Google Scholar
  9. https://pdfs.semanticscholar.org/1d58/77a039852e2a97ac3cb74ce8cdbff634013c.pdf and
     Google Scholar
  10. https://www.ajol.info/index.php/mjz/article/viewFile/142808/132555 (Accessed on 5th May, 2020).
     Google Scholar
  11. Tsarkov, A., & Petlovanyi, P. (2016). Bipolar disorder in child psychiatric practice. Available at: https://library.adhl.africa/handle/123456789/11623 (Accessed on 5th May, 2020).
     Google Scholar
  12. Tylee, A., Gastpar, M., Lepine, J. P. & Mendlewicz, J. (1999). DEPRES II (Depression Research in European Society II): a patient survey of the symptoms, disability and current management of depression in the community. DEPRES Steering Committee. Int. Clin. Psychopharmacology, 14(3): 139-51.
    DOI  |   Google Scholar
  13. Sadock, B. J., Sadock, V. A. & Ruiz, P. (2014). Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry (11th Edition). LWW.
     Google Scholar
  14. Al-Harbi, K. S. (2012). Treatment-resistant depression: therapeutic trends, challenges, and future directions. Patient Prefer Adherence, 6: 369–388.
    DOI  |   Google Scholar
  15. Phiri, C., Tsarkov, A., Petlovanyi, P., & Lingenda, G. Factors Contributing To Oral Diseases and Treatment Needs amongst Mental Patients at Chainama Hills College Hospital, Lusaka, Zambia. Available at: https://pdfs.semanticscholar.org/eb6c/a411d94f5adeb7f68fdaa3c728aad2038f85.pdf and https://www.onlinejournal.in/IJIRV3I11/081.pdf (Accessed on 5th May, 2020).
     Google Scholar
  16. Schimelpfening, N. (2019). The History of Depression: Accounts, treatments, and beliefs through the ages. “Very well mind”. Available at: https://www.verywellmind.com/who-discovereddepression-1066770 (Accessed on 9th May,2020).
     Google Scholar
  17. Horwitz, A. V. (2010). How an Age of Anxiety Became an Age of Depression. Milbank Q., 88(1): 112–138.
    DOI  |   Google Scholar
  18. Ramachandraih, C. T., Subramanyam, N., Bar, K. J., Baker, G. & Yeragani, V. K. (2011). Antidepressants: From MAOIs to SSRIs and more. Indian J. Psychiatry, 53(2): 180–182.
    DOI  |   Google Scholar
  19. Tsarkov, A., & Petlovanyi, P. (2017). Omega-3 Fatty Acids as an Alternative Treatment for Children with Attention Deficit Hyperactivity Disorder. Imperial Journal of Interdisciplinary Research (IJIR), 3, 1378-1380. Available at: https://pdfs.semanticscholar.org/42bd/c75304c050d502670c7e8c86fddf5f5079ce.pdf and http://www.onlinejournal.in/IJIRV3I2/237.pdf (Accessed on 9th May, 2020).
     Google Scholar
  20. Tsarkov, A., & Petlovanyi, P. Pathological Gambling: The Old Problem of the Modern World. Available at: https://www.semanticscholar.org/paper/Pathological-Gambling%3A-The-Old-Problem-of-the-World-Tsarkov-Petlovanyi/107eadfc25a12d61e999daa8e9799f60ba9e026f and http://www.onlinejournal.in/IJIRV3I8/034.pdf (Accessed on 9th May, 2020).
     Google Scholar
  21. Stahl, S. M., Grady, M. M., Moret, C. & Briley, M. (2005). SNRIs: The Pharmacology, Clinical Efficacy, and Tolerability in Comparison with Other Classes of Antidepressants. Cambridge University Press, 10(9): 732-747.
    DOI  |   Google Scholar