The Prevalence of Rheumatoid Arthritis in the Elderly that attend Pilgrimage Centre, Elele, Nigeria
Article Main Content
This study determined the prevalence of Rheumatoid arthritis in elderly people that attended pilgrimage center, Elele Rivers state, Nigeria. A total of 200 subjects attending the pilgrimage center were examined for Rhematoid Factor using Latex agglutination method. The data was subjected to statistical analysis using Statistical Package for Social Sciences (SPSS) version 16.0. A prevalence of 4% was seen in the female subjects within the age bracket of 65-80 years and a prevalence of 1% was seen in the male subjects within the age bracket of 61-70 years. It showed that Rheumatoid arthritis was positive in 5% of the population and negative in 95% of the population, which was statistically significant (p< 0.05). In conclusion, there is a significant increase in the overall prevalence of rheumatoid arthritis in elderly subjects that attend pilgrimage center, Elele. Therefore proper care should be instituted to avoid unnecessary complications associated with this ailment.
References
-
O. O. Adelowo, O. Ojo, I. Oduenyi, and C. C. Okwara, “Rheumatoid arthritis among Nigerians: the first 200 patients from a rheumatology clinic”, Clinical Rheumatology, vol. 29 (6), pp. 593-597, 2011.
DOI |
Google Scholar
1
-
D. Antin-Ozerkis, J. Evans, A, Rubinowitz, R. J. Homer, and R. A. Matthay, “Pulmonary manifestations of rheumatoid arthritis”, Clinics in Chest Mediciine, vol. 31(14), pp. 451-478, 2010.
DOI |
Google Scholar
2
-
J. A. Aviña-Zubieta, H. K. Choi, M. Sadatsafavi, M. Etminan, J. M. Esdaile and D. Lacaille, “Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies”, Arthritis and Rheumatism, vol. 59(12), pp. 1690-1697, 2008.
DOI |
Google Scholar
3
-
H. F. Bastian, “Therapeutic strategies in rheumatoid arthritis”, Internist, vol. 52 (6), pp. 645-656, 2011.
DOI |
Google Scholar
4
-
P. Beighton, L. Solomon and H. A. Valkenburg, “Rheumatoid arthritis in a rural South African Negro population”, Annals of Rheumatologic Discussions, vol. 34(2), pp. 136-141, 1975.
DOI |
Google Scholar
5
-
S. W. Brighton, A. L. de la Harpe, D. J. van Staden, J. H. Badenhorst and O. L. Myers, “The prevalence of rheumatoid arthritis in a rural African population”, Journal of Rheumatology, vol. 15(3), pp. 405-408, 1988.
Google Scholar
6
-
Y. G. Chiu & C.T. Ritchlin, “Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis” Expert Opinion on Biological Therapy, vol. 17(1), pp. 119-128, 2017.
DOI |
Google Scholar
7
-
B. Dowan, R.M. Campbell, L. Zgaga, D. Adeloye and K.Y. Chan, “Estimating the burden of rheumatoid arthritis in Africa”, The Journal of Global Health, vol. 2(2), pp. 020-406, 2012.
DOI |
Google Scholar
8
-
G. S. Firestein, “Evolving concepts of rheumatoid arthritis”, Nature, vol. 423(6937), pp. 356-361, 2003.
DOI |
Google Scholar
9
-
A. Gupta and& B. Fomberstein, “Evaluating cardiovascular risk in rheumatoid arthritis”, Journal of Musculoskeletal Medicine, vol. 26(8), pp. 481-494, 2009.
Google Scholar
10
-
M. Kaddu-Mukasa, E. Ssekasanvu, E. Ddumba, D. Thomas and E.T. Katabira, “Rheumatic manifestations among HIV positive adults attending the Infectious Disease Clinic at Mulago Hospital”, African Health Science, vol. 11(1), pp. 24-29, 2011.
Google Scholar
11
-
K. P. Liao and D.H. Solomon, “Traditional cardiovascular risk factors, inflammation and cardiovascular risk in rheumatoid arthritis”, Rheumatology, vol. 52, pp. 45-52, 2013.
DOI |
Google Scholar
12
-
J. J. Malemba, J. M. Mbuyi-Muamba, J. Mukaya, X. Bossuyt, M. P. Emonds, K. Deiteren and J. Muamba, “The phenotype and genotype of rheumatoid arthritis in the Democratic Republic of Congo”, Arthritis Research Therapy, vol. 15(4), pp. 89-92, 2013.
DOI |
Google Scholar
13
-
J. J. Malemba, J. Mbuyi-Muamba, J. Mukaya, X. Bossuyt, P. Verschueren, R. Westhovens and R.M. Campbell, “The epidemiology of rheumatoid arthritis in Kinshasa, Democratic Republic of Congo—a population-based study”, Rheumatology (Oxford), vol. 51(9), pp. 1644-1647, 2012.
DOI |
Google Scholar
14
-
O. L. Meyers, S. Jessop, and P. Klemp, “The epidemiology of rheumatic disease in a rural and an urban population over the age of 65 years”, South African Medicial Journal, vol. 62(12), pp. 403-405, 1982.
Google Scholar
15
-
J. D. Moolenburgh, H. A. Valkenburg, and P. B. Fourie, “A population study on rheumatoid arthritis in Lesotho, southern Africa”, Annals of Rheumatologic Discussions, vol. 45(8), p. 691-695, 1986.
DOI |
Google Scholar
16
-
K. Nishimura, D. Sugiyama, Y. Kogata, G. Tsuji, T. Nakazawa, S. Kawano & S. Kumagai, “Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthriti"s”, Annals of Internal Medicine, vol. 146(11), pp. 797-808, 2007.
DOI |
Google Scholar
17
-
B. Shah and A. Ankur, Harrison's Principles of Internal Medicine (18th edition), United States: McGraw Hill. 2012, p. 324-327.
Google Scholar
18
-
M. Singwe-Ngandeu, J. Meli, H. Ntsiba, C. Nouedoui, A. V. Yollo, M. B. Sida and D. Thomas, “Rheumatic diseases in patients attending a clinic at a referral hospital in Yaounde, Cameroon”, Eastern Africa Medical Journal, vol. 84(9),pp. 404-409, 2007.
DOI |
Google Scholar
19
-
S. Slimani and A. Ladjouze-Rezig, “Prevalence of rheumatoid arthritis in an urban population of Algeria: a prospective study”, Rheumatology, vol. 53(3), pp. 571-573, 2014.
DOI |
Google Scholar
20
-
J. S. Smolen, D. Aletaha and I. B. McInnes, “Rheumatoid arthritis”, The Lancet, vol. 388(10055), pp. 2023-2038, 2016.
DOI |
Google Scholar
21
-
D. H. Solomon, N. J. Goodson, J. N. Katz, M. E. Weinblatt, J. Avorn, and S.A. Setoguchi, “Patterns of cardiovascular risk in rheumatoid arthritis”, Annals of the Rheumatic Diseases, vol. 65(12), pp. 1608-1612, 2006.
DOI |
Google Scholar
22
-
L. Solomon, G. Robin and H.A. Valkenburg, “Rheumatoid arthritis in an urban South African Negro population” Annals of Rheumatologic Discussion, vol. 34(2), pp. 128-135, 1975.
DOI |
Google Scholar
23
-
L. Solomon, H. A. Valkenburg, P. Beighton, G. Robin and C. L. Soskolne, “Rheumatic disorders in the South African Negro. Part I. Rheumatoid arthritis and ankylosing spondylitis”, South African Medical Journal, vol. 49(32), pp. 1292-1296, 1975.
Google Scholar
24
-
O. M. Westwood, P. N. Nelson and F. C. Hay, “Rheumatoid factors: what's new?”, Rheumatology, vol. 45(4), pp. 379-385, 2006.
DOI |
Google Scholar
25
-
F. Wolfe, D. M. Mitchell, J. T. Sibley, J. F. Fries, D. A. Bloch, C. A. Williams and M. A. Cathey, “The mortality of rheumatoid arthritis” Arthritis and Rheumatism, vol. 37(4), pp. 481-494, 1994.
DOI |
Google Scholar
26