Neuroendocrine Tumor of the Appendix (A Case Report)
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Neuroendocrine tumours (NETs) are characterised by their ability to secrete hormones. There is a wide variety of NETs that can develop in any organ of the digestive system. NETs of the appendix are rare with an estimated incidence of 0.15 to 06 cases/year per 100,000 people and are often seen in young adults with a male predominance. Most NETs of the appendix are asymptomatic and usually discovered incidentally during appendectomy. Treatment is by surgical removal of the tumour to a healthy margin in accordance with the principles of carcinology.
We report on a case of a 24-year-old female patient. She was admitted with generalized abdominal pain originating in the right iliac fossa with a B.P. of 0 and a fever of 38°C. The abdominal and pelvic CT scan showed acute appendicitis with a discrete agglutination of the loop around the appendix and an effusion of the right iliac fossa and pelvis of medium abundance. The biological work-up showed a hyperleukocytosis with a predominance of neutrophils. The patient underwent ileo-caecal resection, ileo-colostomy in double gun barrel after an exploration which revealed a mass of appendicular cystic appearance "suspicion of appendicular mucocele?" with a purulent peritoneal effusion and false membranes in the inter-anses. Pathological examination showed a proliferation of organoid architecture suggestive of a neuroendocrine tumour measuring 4 mm in length.
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References
-
Bayhan Z, Yildiz YA, Akdeniz Y, Gonullu E, Altintoprak F, Mantoglu B, et al. Appendix Neuroendocrine Tumor: Retrospective Analysis of 4026 Appendectomy Patients in a Single Center. Emergency Medicine International. 2020; 2020: 1‑6.
DOI |
Google Scholar
1
-
Morais C, Silva E, Brandão PN, Correia R, Foreid S, Valente V. Neuroendocrine tumor of the appendix—a case report and review of the literature. Journal of Surgical Case Reports. 2019(3).
DOI |
Google Scholar
2
-
Néoplasies Neuroendocrines (NNE) digestives. Société Nationale Française de Gastro-Entérologie. [Internet]. Available from: https://www.snfge.org/content/11-neoplasies-neuroendocrines-nne-digestives. French.
Google Scholar
3
-
Meyer DJ, Balaphas A, Koessler T, Morel PP, Bühler L, Buchs DN. Les tumeurs de l’appendice et leur prise en charge. Revue Médicale Suisse. 2018; 5. French.
DOI |
Google Scholar
4
-
Bahi L, Oqbani K, Karich N, Mounhoub M. Tumor of the Appendix: A Case Report. International Journal of Advanced Research. 2018; 6(11): 697-701.
DOI |
Google Scholar
5
-
Dousset B. Traitement chirurgical des tumeurs endocrines du tube digestif. La Lettre de L’hépato-Gastroentérologue.2006; 1(IX): 32-35. French.
Google Scholar
6
-
Hof KH, van der Wal HC, Kazemier G, Lange JF. Carcinoid Tumour of the Appendix: An Analysis of 1,485 Consecutive Emergency Appendectomies. J Gastrointest Surg. 2008; 12(8): 1436‑8.
DOI |
Google Scholar
7
-
Pickhardt PJ, Levy AD, Rohrmann CA, Kende AI. Primary Neoplasms of the Appendix: Radiologic Spectrum of Disease with Pathologic Correlation. RadioGraphics. 2003; 23(3): 645‑62.
DOI |
Google Scholar
8
-
Ploenes T, Börner N, Kirkpatrick CJ, Heintz A. Neuroendocrine Tumour, Mucinous Adenocarcinoma and Signet-Ring Cell Carcinoma of the Appendix: Three Cases and Review of Literature. Indian J Surg. 2013; 75(S1): 299‑302.
DOI |
Google Scholar
9
-
Griniatsos J. Appendiceal neuroendocrine tumors: Recent insights and clinical implications. WJGO. 2010; 2(4): 192.
DOI |
Google Scholar
10
-
Tchana-Sato V. Carcinoid tumor of the appendix: A consecutive series from 1237 appendectomies. WJG. 2006; 12(41): 6699.
DOI |
Google Scholar
11
-
Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer. 2003; 97(4): 934‑59.
DOI |
Google Scholar
12
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