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The vagina of a woman is a sophisticated microecology system. Typically, the H2O2-producing Lactobacillus dominates the vaginal microbiota of healthy women. This bacterium converts glycogen in vaginal epithelial cells into lactic acid, sustaining the vagina's natural acidic environment. Understanding the substantial correlation between the vaginal and upper genital tract microbiota and vaginal and genital tract infections has led to an interest in these areas. However, the spectrum of microbial types consistent with a functioning genital tract and the variables influencing the flora remains perplexing. The most prevalent gynecological condition seen in primary care, vaginitis caused by Candida albicans, is a significant public health concern due to its high frequency. Candidal vulvovaginitis, also known as vaginal thrush and vaginal yeast infection, is an overgrowth of yeast in the vagina that irritates. Ozone treatment has made its way into German medical practice, where it is successfully applied to treat several disorders. Medical ozone's qualities, such as its bactericidal, virucidal, fungicidal, analgesic, and other effects, have been utilized in therapy, surgery, obstetrics and gynecology, dermatology, stomatology, and the treatment of infectious and venereal illnesses. During ozone treatment or therapy, a catheter was used to insufflate an ozone/oxygen gas mixture into the female reproductive system. They were completed continuously by attaching a catheter to the ozone output hose and allowing the ozone/oxygen gas mix to flow for the allotted time. Based on clinical and microbiological evidence, the effectiveness standards Complete clinical and microbiological recovery observable clinical symptoms that are objective. The vaginal mucous membrane was free of inflammatory disorders following treatment, and vaginal cultures were negative.

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