Central serous chorioretinopathy (CRSC) is a pathology of the retina and the choroid characterized by a vanishing point causing sub-retinal fluid accumulation and focal retinal detachment.
We report a case of a 40-year-old male patient followed for 5 years in dermatology for psoriasis treated with topical corticosteroids who presented to the emergency department for a visual acuity at 3/10 in his right eye associated with a macular syndrome.
Several cases of corticosteroid-induced CRSC were found in the literature, but only few cases were found after application of topical corticosteroid. Optical coherence tomography was performed urgently and revealed central serous chorioretinitis. Treatment with topical corticosteroids was discontinued. The patient was seen a week later, with visual acuity recovery from 3/10 to 10/10, with improvement in macular syndrome.
Nadeau S, Nguyen F, Guigou S. Choriorétinite séreuse centrale et tadalafil, à propos d’un cas. J Fr Ophtalmol. 2012; 35(2): 121.e1-121.e5. French.
Jalkh AE, Jabbour N, Avila MP, Trempe CL, Schepens CL. Retinal pigmnet epithelium descompensation. I Clinical features and natu- ral course. Ophthalmology. 1984;91:1544-8.
Bouzas EA, Karadimas P, Pournaras CJ. Central serous chorioretinopathy and glucocorticoids. Surv Ophthalmol. 2002; 47: 431–448.
Tsai DC, Chen SJ, Huang CC, Chou P, Chung CM, Chan WL, et al. Risk of central serous chorioretinopathy in adults prescribed oral corticosteroids: a population-based study in Taiwan. Retina. 2014; 34: 1867–1874.
Zhao M, Célérier I, Bousquet E, Jeanny JC, Jonet L, Savoldelli M, et al. Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy. J Clin Invest. 2012; 122: 2672–2679.
Polak BC, Baarsma GS, Snyer B. Diffuse retinal pigment epithelio- pathy complicating systemic corticosteroid treatment. Br J Ophthal- Mol. 1995; 79: 922-5.
Chan WM, Lai TY, Lai RY, Liu DT, Lam DS. Half-dose verteporfin photodynamic therapy for acute central serous chorioretinopathy: one-year results of a randomized controlled trial. Ophthalmology. 2008; 115(10): 1756-65.
This work is licensed under a Creative Commons Attribution 4.0 International License.