Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration

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  •   Tariq Mehmood Dar

  •   Kashif Ali Samin

Abstract


Background: The socioeconomic burden on society grows as the incidences of chronic age-related degenerative diseases increase which demand extensive wound care as well. To speed up the healing of cutaneous wounds, new wound healing treatments must be researched, trialed & developed. Regeneration therapies are gaining popularity since they are less invasive than other treatments.




Method: Published research paper have been reviewed to develop a concept and analyze the role of Platelet-rich plasma (PRP) and Growth factors-rich plasma in speedy wound healing and tissue regeneration. Three patients with diabetic ulcers have been selected and applied Growth factors-rich plasma and membrane treatment on weekly basis and analyzed the results.




Results: Growth factors-rich plasma injection and membrane application on wound have produced remarkable wound healing outcome within 3 to 6 applications with new vascularization and re-epithelialization. 




Conclusion: Growth factors-rich plasma and membrane application on wound gained favor as a wound-healing therapy due to its constituents which have remarkable potential to speed up the injured tissue repair and regeneration. The release of cytokines with platelet-derived growth molecules enveloped in alpha-granule, promote & facilitate wound healing.



Keywords: Alpha-granule, degenerative diseases, growth factors-rich plasma, platelet-derived growth factors, wound healing process

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How to Cite
Dar, T. M., & Samin, K. A. (2021). Role of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration. European Journal of Medical and Health Sciences, 3(6), 14–23. https://doi.org/10.24018/ejmed.2021.3.6.1105