Rhabdomyolysis and Obstetric Correlates: Literature Perspectives for the Obstetric Anesthesiologist


  •   Rabiu Momoh


Rhabdomyolysis complicating the antepartum or peripartum period is not a commonly reported finding and where they occur, it can be life-threatening. The problem with rhabdomyolysis during pregnancy or labour is the potential harmful systemic and local effects it can cause. These includes cardiac arrhythmias, acute kidney injury, clotting problems in severe cases [1]. To the fetus, foetal distress or foetal demise could be the end-result where timely management is not initiated [2].

Keywords: Creatine kinase, gluteal compartment syndrome, labour, neuraxial analgesia, pregnancy, rhabdomyolysis


P. A. Torres, J. A. Helmstetter, A. M. Kaye and D. K. Alan, “Rhabdomyolysis: pathogenesis, diagnosis, and treatment. Ochsner Journal 15(1): 58-69, 2015.

B. V. Li, D. A. Strong and H. M. Esdale, “Recurrent severe rhabdomyolysis in a pregnancy affected by myotonic dystrophy type 1,” Pathology 52, S98, 2020.

J. M. Sauret, G. Marinides and G. K. Wang, “Rhabdomyolysis,” American Family Physician 65(5): 907-12, 2002.

R. Momoh, T. Sherica and S. Reddy, “A Case of Rhabdomyolysis in A Pregnant Patient During Labor” https://cdn.technologynetworks.com/ep/pdfs/a-case-of-rhabdomyolysis-in-a-pregnant-patient-during-labor.pdf

N. Petejova and A. Martinek, “Acute kidney injury due to rhabdomyolysis and renal replacement therapy: a critical review,” Critical Care 18(3): 224, 2014.

Y. S. Chatzizisis, G. Misirli, A. I. Hatzitolios and G. D. Giannoglou, “The syndrome of rhabdomyolysis: complications and treatment,” European Journal of Internal Medicine 19(8): 568-574, 2008.

M. Srisuttayasathien, “A Case of Hypokalemia-Induced Rhabdomyolysis as a result of Distal Renal Tubular Acidosis in a Pregnant Woman: A Case Report and Literature Review,” Hindawi Journal Volume 2015.

G. Carminati, A. Chena, J. M. Orlando, S. Russo, S. Salomón and J. A. Carena, “A case series on the incidences of distal renal tubular acidosis with rhabdomyolysis as the presenting form in 4 pregnant women,” https://europepmc.org/article/med/11464655.

Wikipedia contributors. Rhabdomyolysis. Wikipedia, The Free Encyclopedia. https://en.wikipedia.org/w/index.php?title=Rhabdomyolysis&oldid=1041819195.

D. Yürük, A. Yilmaz, G. E. Özgencil and İ. Aşik: “A Case Report: Acute rhabdomyolysis following epidural steroid injection: An unusual complication in a patient with low back pain,” Agri 31(3): 150-152, 2019.

K. Nasu, T. Sugano, J. Yoshimatsu and H. Narahara, “Rhabdomyolysis Caused by Tocolysis with Oral Ritodrine Hydrochloride in a Pregnant Patient with Myotonic Dystrophy,” Gynecologic and Obstetric Investigation 61(1): 53-55, 2006.

E. C. Lampley, S. Williams, S. A. Myers, “Cocaine-associated rhabdomyolysis causing renal failure in pregnancy,” Obstetrics & Gynecology, 87(5): 804-806, 1996.

C. A. Grotegut, V. Dandolu, S. Katari, V. E. Whiteman, O. Geifman-Holtzman and M. Teitelman, “Baking soda pica: a case of hypokalemic metabolic alkalosis and rhabdomyolysis in pregnancy,” Obstetrics & Gynecology 107(2): 484-486, 2006.

K. M. S. Childress and T. Myles, “Baking soda pica associated with rhabdomyolysis and cardiomyopathy in pregnancy,” Obstetrics & Gynecology 122(2): 495-497, 2013.

V. Kumar, K. Saeed, A. Panagopoulos and P. J. Parker, “Gluteal compartment syndrome following joint arthroplasty under epidural anaesthesia: a report of 4 cases,” Journal of Orthopaedic Surgery 15(1): 113-117, 2007.

R. J. Pacheco, S. Buckley, N. J. Oxborrow, A. C. Weeber and K. Allerton, “Gluteal compartment syndrome after total knee arthroplasty with epidural postoperative analgesia,” The Journal of Bone and Joint Surgery 83(5): 739-740, 2001.

D. Barick and A. Nemade, “Bilateral post-traumatic gluteal compartment syndrome: A case report and review of literature,” Journal of Orthopaedics and Allied Sciences, 3(1): 33, 2015.

A.Smith, V. Chitre and H. Deo, “Acute gluteal compartment syndrome: superior gluteal artery rupture following a low energy injury,” Case Reports, bcr2012007710, 2012.

H. L. Liu and D. S. Wong, “Gluteal compartment syndrome after prolonged immobilization,” Asian Journal of Surgery 32(2): 123-126, 2009.

T. Klockgether, M. Weller, T. Haarmeier, B. Kaskas, G. Maier and J. Dichgans, “Gluteal compartment syndrome due to rhabdomyolysis after heroin abuse,” Neurology 48(1): 275-276, 1997.

G. Via, F. Oliva, M. Spoliti and N. Maffulli, “Acute compartment syndrome,” Muscles, Ligaments and Tendons Journal 5(1): 18, 2015.


Download data is not yet available.


How to Cite
Momoh, R. (2021). Rhabdomyolysis and Obstetric Correlates: Literature Perspectives for the Obstetric Anesthesiologist. European Journal of Medical and Health Sciences, 3(6), 1–3. https://doi.org/10.24018/ejmed.2021.3.6.1098